Ayman Al-Hendy Selected Research

Leiomyoma (Uterine Fibroids)

5/2022	Report of Exosomes Isolated from a Human Uterine Leiomyoma Cell Line and Their Impact on Endometrial Vascular Endothelial Cells.
4/2022	Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with uterine fibroids.
3/2022	An evaluation of relugolix/estradiol/norethindrone acetate for the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.
2/2022	Epigenetic Regulation in Uterine Fibroids-The Role of Ten-Eleven Translocation Enzymes and Their Potential Therapeutic Application.
1/2022	Reduction of Heavy Menstrual Bleeding in Women Not Designated as Responders to Elagolix Plus Add Back Therapy for Uterine Fibroids.
1/2022	Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment.
1/2022	Relugolix Combination Therapy for Uterine Leiomyoma-Associated Pain in the LIBERTY Randomized Trials.
1/2022	Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-β3 and Wnt/β-Catenin pathways.
1/2022	Adverse childhood experiences and health-related quality of life among women undergoing hysterectomy for uterine leiomyoma.
11/2021	What We Know about the Long-Term Risks of Hysterectomy for Benign Indication-A Systematic Review.

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Ayman Al-Hendy Research Topics

Disease

101	Leiomyoma (Uterine Fibroids) 05/2022 - 05/2004
36	Neoplasms (Cancer) 01/2022 - 11/2004
9	Menorrhagia 04/2022 - 11/2018
8	Inflammation (Inflammations) 01/2021 - 04/2014
7	Infertility (Sterility) 10/2021 - 01/2012
7	Endometriosis 10/2021 - 08/2007
6	Fibrosis (Cirrhosis) 01/2022 - 04/2011
6	Amenorrhea 01/2021 - 01/2012
5	Hemorrhage 01/2022 - 01/2019
4	Premature Birth (Birth, Premature) 11/2018 - 12/2007
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022 - 02/2007
3	Pain (Aches) 01/2022 - 01/2019
3	Vitamin D Deficiency 01/2021 - 01/2013
3	Endometrial Neoplasms (Endometrial Cancer) 01/2013 - 02/2008
3	Breast Neoplasms (Breast Cancer) 01/2009 - 11/2007
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 04/2022 - 05/2008
2	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2016
2	Leiomyosarcoma 12/2020 - 01/2020
2	Primary Ovarian Insufficiency 07/2020 - 09/2018
2	Body Weight (Weight, Body) 01/2018 - 08/2015
2	Hypoxia (Hypoxemia) 01/2017 - 09/2014
2	Obesity 01/2013 - 12/2011
2	B-Cell Lymphoma (Lymphoma, B Cell) 12/2011 - 09/2008
1	Uterine Neoplasms (Uterine Cancer) 01/2022

Drug/Important Bio-Agent (IBA)

27	Estrogens (Estrogen)FDA Link 10/2021 - 11/2004
13	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2006
11	Vitamin D FDA LinkGeneric 01/2021 - 01/2011
8	Hormones (Hormone)IBA 01/2022 - 02/2016
8	Cholecalciferol (Vitamin D3)FDA Link 01/2021 - 04/2011
8	Progesterone FDA LinkGeneric 01/2020 - 10/2007
8	Estrogen ReceptorsIBA 01/2017 - 11/2004
7	Estradiol (Delestrogen)FDA LinkGeneric 04/2022 - 01/2009
7	Endocrine DisruptorsIBA 01/2021 - 01/2016
7	CytokinesIBA 10/2020 - 08/2007
7	Calcitriol (Calcijex)FDA LinkGeneric 01/2019 - 04/2011
6	Biomarkers (Surrogate Marker)IBA 05/2022 - 04/2008
6	Norethindrone Acetate (Norlutate)FDA LinkGeneric 04/2022 - 01/2020
6	Biological ProductsIBA 01/2022 - 02/2006
6	elagolixIBA 01/2022 - 11/2018
6	Mediator ComplexIBA 01/2020 - 04/2015
6	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2014 - 02/2006
5	Gonadotropin-Releasing Hormone (GnRH)FDA Link 04/2022 - 01/2020
5	Pharmaceutical PreparationsIBA 03/2022 - 01/2018
5	Simvastatin (Zocor)FDA LinkGeneric 01/2022 - 12/2014
5	CateninsIBA 01/2022 - 01/2016
5	Progesterone Receptors (Progesterone Receptor)IBA 01/2018 - 10/2007
5	Caspase 3 (Caspase-3)IBA 01/2017 - 11/2004
5	Proliferating Cell Nuclear Antigen (PCNA)IBA 04/2016 - 10/2007
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2016 - 12/2006
5	Cyclin D1IBA 04/2012 - 12/2006
5	catechol (pyrocatechol)IBA 09/2008 - 07/2006
4	relugolixIBA 03/2022 - 01/2021
4	SteroidsIBA 10/2021 - 01/2019
4	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2016
4	DNA (Deoxyribonucleic Acid)IBA 12/2020 - 09/2008
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2020 - 09/2008
4	ulipristal acetate FDA Link 01/2020 - 01/2018
4	TeaIBA 01/2014 - 03/2010
4	TransferasesIBA 09/2008 - 07/2006
3	AndrogensIBA 04/2022 - 08/2014
3	Diethylstilbestrol (Stilbestrol)FDA Link 12/2020 - 01/2016
3	VitaminsIBA 08/2020 - 02/2014
3	Steroid Receptors (Steroid Receptor)IBA 01/2018 - 04/2015
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2016 - 04/2008
3	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2014 - 03/2010
3	2-MethoxyestradiolIBA 01/2009 - 12/2006
2	EnzymesIBA 02/2022 - 01/2019
2	Long Noncoding RNAIBA 01/2022 - 01/2019
2	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 01/2021 - 11/2018
2	MethyltransferasesIBA 12/2020 - 01/2014
2	Therapeutic UsesIBA 10/2020 - 04/2012
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 02/2016
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 07/2006
2	ulipristalIBA 01/2020 - 01/2018
2	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2020 - 04/2012
2	RNA (Ribonucleic Acid)IBA 01/2019 - 07/2015
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2017 - 08/2008
2	BerberineIBA 01/2017 - 04/2015
2	Transforming Growth Factor beta (TGF-beta)IBA 12/2016 - 01/2014
2	ChromatinIBA 10/2016 - 03/2016
2	Polycomb-Group ProteinsIBA 10/2016 - 03/2016
2	GenisteinIBA 07/2016 - 01/2016
2	paricalcitol (Zemplar)FDA Link 09/2015 - 09/2014
2	CalciumIBA 12/2014 - 01/2013
2	Calcitriol Receptors (Calcitriol Receptor)IBA 09/2014 - 12/2013
2	1,25-dihydroxyvitamin DIBA 02/2014 - 04/2011
2	CollagenIBA 01/2014 - 12/2006
2	Matrix Metalloproteinases (MMPs)IBA 09/2013 - 10/2007
2	AdipokinesIBA 01/2013 - 12/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2009 - 10/2008
2	Ganciclovir (Cytovene)FDA LinkGeneric 01/2009 - 07/2006
2	Thymidine KinaseIBA 01/2009 - 07/2006
1	Peptides (Polypeptides)IBA 01/2022
1	ProteomeIBA 01/2022
1	DyeCycle VioletIBA 01/2022

Therapy/Procedure

26	Therapeutics 03/2022 - 05/2004
13	Hysterectomy 01/2022 - 11/2004
5	Drug Therapy (Chemotherapy) 01/2021 - 01/2018
2	Uterine Myomectomy 01/2016 - 04/2012
2	Aftercare (After-Treatment) 01/2010 - 01/2009